Thalassemia is inherited with major phenomenon pale, stomach appear grow because spleen swelling and heart, when not been cured nicely would happen facial bone distortion and skin colour become black. This causes of disease are lacking wrong maker a nutrient haemoglobin (Hb) until production haemoglobin decrease.
Disease thalassemia due to be difference / change / mutation to gene globin alpha or gene globin until production chain globin stated decrease or there was no. Consequently Hb's production decrease and red blood cell easy once damaged or his age shorter from blood cell normal (120 day). When difference to gene globin alpha then his disease mentioned thalassemia alpha, whereas difference to gene globin will cause disease thalassemia.
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